BDBM31826 4-aminoquinazoline, 2a::BMC163482 Compound 3::CHEMBL188762

SMILES CCC(=O)Nc1ccc2ncnc(Nc3cccc(Br)c3)c2c1

InChI Key InChIKey=WUPUZEMRHDROEO-UHFFFAOYSA-N

Data  8 IC50  1 Other

PDB links: 2 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 31826   

TargetEpidermal growth factor receptor [668-1210](Homo sapiens (Human))
Chemical Genomics Centre of The Max Planck Society

LigandPNGBDBM31826(4-aminoquinazoline, 2a | BMC163482 Compound 3 | CH...)
Affinity DataIC50:  0.430nMpH: 7.5 T: 2°CAssay Description:The kinase reaction for EGFR consisted of BSA-supplemented kinase buffer, kinase, peptide, and ATP. For IC50 determinations, 10 different concentrati...More data for this Ligand-Target Pair